Anti-Human CD245 Mab (Clone:DY12)
Specificity: The mouse monoclonal antibody DY12 recognizes an extracellular epitope of CD245, a transmembrane protein expressed mainly by peripheral blood lymphocytes, NK cells, monocytes, granulocytes and platelets. CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.
Product Specifications
Product Name Alternative
P220/240, DY12, DY35
Host
Mouse
Immunogen
Human NK-type YT2C2 cells
Target Antigen
CD245
Clonality
Monoclonal
Clone
DY12
Applications
IP, IHC, FACS, WB
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide. Concentration : 1 mg/mL
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Isotype
Mouse IgG1 kappa
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
