Anti-Human CD316 MAb (Clone :8A12)
Specificity: The mouse monoclonal antibody 8A12 recognizes an extracellular epitope of CD316, a type I transmembrane glycoprotein, expressed mainly by lymphocytes, NK cells and in a broad range of tissues. CD316 is an approximately 63 kDa transmembrane glycoprotein, which forms stable complexes with CD9, as well as with CD81. It seems that CD316 participates in regulation of cell polarity and motility, in cell proliferation, oocyte fertilization and tumor cell metastasis. It is expressed mainly by lymphocytes, NK cells and in a broad range of tissues, and associates with actin cytoskeleton.
Product Specifications
Product Name Alternative
Immunoglobulin superfamily member 8, EWI2, PGRL, KCT-4, LIR-D1, IGSF8
Gene Name
IGSF8
Gene ID
93185
UniProt
Q969P0
Host
Mouse
Reactivity
Human
Immunogen
Human leukocytes
Target Antigen
CD316
Clonality
Monoclonal
Clone
8A12
Applications
IP, IHC, FACS
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
1 mg/mL Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow cytometry: Recommended dilution: 1-5 μg/mL
Isotype
Mouse IgG2a
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