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Anti-Hu CD218a Purified

CD218a, an approximately 62 kDa type I transmembrane glycoprotein, is the alpha subunit of IL-18 receptor heterodimer. It is expressed in various immune cells, including lymphocytes, NK cells, and myeloid cells, as well as in heart, lung, liver, gut and another tissues. IL-18 is a proinflammatory cytokine, that promotes both Th1 and Th2 immune responses, induces IFN-gamma production and activates NK cells.Specificity :The mouse monoclonal antibody H44 recognizes an extracellular epitope of CD218a, the alpha subunit of IL-18 receptor.

Product Specifications

Product Name Alternative

Interleukin 18 receptor 1 IL18R1, IL-18 R1, IL18-RA

Gene Name

IL18R1

Gene ID

8809

UniProt

Q13478

Reactivity

Human

Immunogen

Human CD218a expressed on a transfected NK0 cell line

Target Antigen

CD218a

Clonality

Monoclonal

Clone

H44

Applications

WB, IHC, FACS, IP, IHC-Fr

Purification

Purified by protein-A affinity chromatography.

Format

Purified

Components

Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 μg/mL.

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