Anti-Hu CD271 Purified
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.Specificity :The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.
Product Specifications
Product Name Alternative
Nerve growth factor receptor TNFRSF16, NGFR, p75NTR, p75NGFR
Gene Name
NGFR
Gene ID
4804
UniProt
P08138
Reactivity
Human, Rabbit, Cat, Non-human primates, Ferret
Immunogen
Purified CD271 protein isolated from human melanoma cell line A875
Target Antigen
CD271
Clonality
Monoclonal
Clone
NGFR5
Applications
FACS, IP, WB, IHC, ICC, MC
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Frequently Asked Questions
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