Anti-Hu CD307d PE

CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG) . Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.Specificity :The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.

Product Specifications

Product Name Alternative

Fc receptor like 4 FcRL4, FCRH4, IRTA1

Gene Name

FCRL4

Gene ID

83417

UniProt

Q96PJ5

Reactivity

Human

Immunogen

DNA-immunization followed by a boost with CD307d-transfected cells

Target Antigen

CD307d

Clonality

Monoclonal

Clone

Applications

FACS

Purification

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Components

Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.