Anti-Hu LOX1 Purified
LOX1, a 31 kDa type II transmembrane protein, is a C-type lectin, functioning as a scavenger receptor for e.g. oxidized low density lipoprotein, apoptotic heat shock proteins, or CRP. It is expressed by macrophages, fibroblasts, platelets, endothelial cells, and smooth muscle cells, and its defects can lead to atherosclerosis. Its expression is enhanced under inflammatory conditions. Multiple splicing variants have been identified. Specificity :The mouse monoclonal antibody 15C4 recognizes an extracellular epitope of LOX1, a C-type lectin transmembrane protein.
Product Specifications
Product Name Alternative
Oxidized low density lipoprotein receptor 1 OLR1, SLOX1, SCARE1, CLEC8A
Gene Name
OLR1
Gene ID
4973
UniProt
P78380
Reactivity
Human
Immunogen
Fusion protein of human LOX1 ectodomain and of human IgG Fc
Target Antigen
LOX1
Clonality
Monoclonal
Clone
15C4
Applications
ICC
Purification
Purified by protein-A affinity chromatography.
Format
Purified
Components
Concentration: 1 mg/mLStorage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow cytometry: Recommended dilution: 1-5 μg/mL
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