Anti-Hu TROP2 Purified

TROP2 is a cell surface receptor that transduces calcium signals. It belongs to carcinoma-associated antigens. Mutations of TROP2 have been associated with gelatinous drop-like corneal dystrophy. Specificity :The mouse monoclonal antibody TrMab-6 recognizes an extracellular epitope of TROP2, a type I transmembrane glycoprotein. This antibody is usefull for detection of TROP2 in breast cancer.

Product Specifications

Product Name Alternative

Tumor associated calcium signal transducer 2 TACSTD2, EGP1, GP50, M1S1, GA733-1

Gene Name

TACSTD2

Gene ID

4070

UniProt

P09758

Reactivity

Pig

Immunogen

TROP2-transfected CHO cells

Target Antigen

TROP2

Clonality

Monoclonal

Clone

TrMab-6

Applications

Purification

Purified by protein-A affinity chromatography.

Format

Purified

Components

Storage Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 μg/mL. Western blotting: Recommended dilution: 1 μg/mL. Immunocytochemistry: Recommended dilution: 10 μg/mL; the cells can be fixed with 4% PFA and permeabilized with 0.1% Triton X-100 before antibody staining, when needed. Immunohistochemistry (paraffin sections) : Recommended dilution: 10 μg/mL. Heat-mediated antigen retrieval in citrate buffer, pH = 6.