Anti-Hu CD307c PE

CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus. Specificity : The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.

Product Specifications

Product Name Alternative

FcRL3, IRTA3

Gene Name

FCRL3

Gene ID

115352

UniProt

Q96P31

Host

Mouse

Reactivity

Human

Immunogen

DNA-immunization followed by a boost with CD307c transfected cells

Target Antigen

CD307c

Clonality

Monoclonal

Clone

Applications

FACS

Purification

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Components

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.