Anti-HDAC6 Antibody (Clone : 178)
Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.Specificity : The mouse monoclonal antibody 178 recognizes zinc finger domain of human histone deacetylase 6 (HDAC6; an intracellular antigen) . Crossreactivity with other species was not tested.
Product Specifications
Product Name Alternative
Histone deacetylase 6, histone deacetylase 6
Gene Name
HDAC6
Gene ID
10013
Reactivity
Human
Immunogen
Human HDAC6
Target Antigen
HDAC6
Clonality
Monoclonal
Clone
178
Applications
ICC, ELISA, IP
Purification
Purified by protein-A affinity chromatography
Format
Purified
Components
1 mg/mLFormulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1 kappa
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