Anti-TNAP Antibody (Clone : W8B2B10)
Tissue non-specific alkaline phosphatase (TNAP), also known as liver/bone/kidney alkaline phosphatase, or MSCA-1 (mesenchymal stem cell antigen 1) is a selective marker for the prospective isolation of bone marrow-derived mesenchymal stem cells and mesenchymal stem-like cells. It is expressed at high levels in liver, bone, kidney, or endometrium, as well as on embryonic stem cells (ESCs) . TNAP also plays a role in bone mineralization. Mutations in TNAP gene are associated with hypercalcemia and skeletal defects (hypophosphatasia) .Specificity : The mouse monoclonal antibody W8B2B10 recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.
Product Specifications
Product Name Alternative
Tissue Non-specific Alkaline Phosphatase, MSCA-1, liver/bone/kidney alkaline phosphatase, alkaline phosphatase, biomineralization associated
Gene Name
ALPL
Gene ID
249
Reactivity
Human
Immunogen
WERI-RB-1 retinoblastoma cell line
Target Antigen
TNAP
Clonality
Monoclonal
Clone
W8B2B10
Applications
ICC, FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Components
1 mg/mLFormulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1
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