Anti-Human CD144/ VE-cadherin Alexa Fluor® 647 Monoclonal Antibody (Clone:55-7H1)
Selected Variant
30-2479-100
Size: 100 Tests
CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.
Product Specifications
Product Name Alternative
Cadherin 5, CDH5, 7B4, VE-cadherin, Vascular endothelial cadherin
Gene Name
CDH5
Gene ID
1003
UniProt
P33151
Host
Mouse
Reactivity
Human
Immunogen
Human endothelial cells.
Target Antigen
CD144
Clonality
Monoclonal
Clone
55-7H1
Applications
ICC, FACS, WB
Purification
The purified antibody is conjugated with Alexa Fluor® 647 under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Format
Purified
Components
Stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Applications Notes
Isotype
Mouse IgG1 kappa
Price
Frequently Asked Questions
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