Anti-CD200 Monoclonal Antibody (Clone:OX-104) -PE Conjugated
CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
Product Specifications
Product Name Alternative
OX-2 membrane glycoprotein, MOX1, MOX2
Gene Name
CD200
Gene ID
4345
UniProt
P41217
Host
Mouse
Reactivity
Human
Immunogen
Human CD200
Target Antigen
CD200
Clonality
Monoclonal
Clone
OX-104
Applications
FACS, IHC, IHC-Fr, Functional Assay
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
PE
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