Anti-CD2 Monoclonal Antibody (Clone:TS1/8) -PE Conjugated
CD2 (also known as LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Product Specifications
Product Name Alternative
T-cell surface antigen CD2, Erythrocyte receptor, T-cell surface antigen T11/Leu-5
Gene Name
CD2
Gene ID
914
UniProt
P06729
Host
Mouse
Reactivity
Human
Immunogen
Cytotoxic T lymphocytes
Target Antigen
CD2
Clonality
Monoclonal
Clone
TS1/8
Applications
FACS, Functional Assay
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
PE
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Fetoprotein, Alpha (AFP, Alpha1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein precursor, FETA, HPAFP) (Biotin)
