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Anti-CD35 / CR1 Monoclonal Antibody (Clone:E11) -PE Conjugated

CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.

Product Specifications

Product Name Alternative

CR1||C3BR

Gene Name

CR1

Gene ID

1378

UniProt

P17927

Host

Mouse

Reactivity

Human, Non-Human Primates

Immunogen

Acute monocytic leukemia cells and normal blood monocytes

Target Antigen

CD35

Clonality

Monoclonal

Clone

E11

Applications

FACS, IP, WB, IHC, IHC-Fr, ICC

Storage Conditions

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.

Isotype

Mouse IgG1

Conjugate

PE

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