Anti-CD35 / CR1 Monoclonal Antibody (Clone:E11) -PE Conjugated
CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.
Product Specifications
Product Name Alternative
CR1||C3BR
Gene Name
CR1
Gene ID
1378
UniProt
P17927
Host
Mouse
Reactivity
Human, Non-Human Primates
Immunogen
Acute monocytic leukemia cells and normal blood monocytes
Target Antigen
CD35
Clonality
Monoclonal
Clone
E11
Applications
FACS, IP, WB, IHC, IHC-Fr, ICC
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
PE
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