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Anti-CD271 / NGFR Monoclonal Antibody (Clone:NGFR5) -PE Conjugated

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Product Specifications

Product Name Alternative

NGFR||TNFRSF16

Gene Name

NGFR

Gene ID

4804

UniProt

P08138

Host

Mouse

Reactivity

Human, Non-Human Primates, Feline, Rabbit, Ferret

Immunogen

Purified CD271 protein isolated from human melanoma cell line A875

Target Antigen

CD271

Clonality

Monoclonal

Clone

NGFR5

Applications

FACS, IP, WB, IHC, ICC

Storage Conditions

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.

Isotype

Mouse IgG1

Conjugate

PE

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