PE Conjugated Anti-IgE Monoclonal Antibody (Clone:BE5)
Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.
Product Specifications
Product Name Alternative
Immunoglobulin heavy constant epsilon
Gene Name
IGHE
UniProt
P01854
Host
Mouse
Reactivity
Human
Immunogen
Purified human IgE.
Target Antigen
IgE
Clonality
Monoclonal
Clone
BE5
Applications
FACS
Components
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Applications Notes
Flow cytometry: Recommended dilution: 2-5 μg/ml.
Isotype
Mouse IgG1
Conjugate
PE
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