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Anti-CD18 / Integrin beta2 subunit Monoclonal Antibody (Clone:M18/2) -FITC Conjugated

CD18, integrin beta2 subunit, forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18) . In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration, mediating intercellular contacts.

Product Specifications

Product Name Alternative

Itgb2

Gene Name

Itgb2

Gene ID

16414

UniProt

P11835

Host

Rat

Reactivity

Mouse

Immunogen

Murine cytotoxic T cell glycoproteins

Target Antigen

CD18 (mouse)

Clonality

Monoclonal

Clone

M18/2

Applications

FACS, IP, WB, IHC, IHC-Fr, Functional Assay

Storage Conditions

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.

Isotype

Rat IgG2a

Conjugate

FITC

Curated Selection

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