Anti-CD271 / NGFR Monoclonal Antibody (Clone:NGFR5) -Biotin Conjugated
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Product Specifications
Product Name Alternative
NGFR||TNFRSF16
Gene Name
NGFR
Gene ID
4804
UniProt
P08138
Host
Mouse
Reactivity
Human, Non-Human Primates, Feline, Rabbit, Ferret
Immunogen
Purified CD271 protein isolated from human melanoma cell line A875
Target Antigen
CD271
Clonality
Monoclonal
Clone
NGFR5
Applications
FACS, IP, WB, IHC, ICC
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1
Conjugate
Biotin
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