Anti-CD45R Monoclonal Antibody (Clone:RA3-6B2) -APC Conjugated
CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
Product Specifications
Host
Rat
Reactivity
Human, Mouse, Feline
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Target Antigen
CD45R (human, mouse)
Clonality
Monoclonal
Clone
RA3-6B2
Applications
FACS, IP, IHC, IHC-Fr, ICC, Functional Assay
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Rat IgG2a
Conjugate
APC
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