Anti-CD140b / PDGF-RB Monoclonal Antibody (Clone:18A2) -APC Conjugated
CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.
Product Specifications
Product Name Alternative
PDGFRB||PDGFR||PDGFR1
Gene Name
PDGFRB
Gene ID
5159
UniProt
P09619
Host
Mouse
Reactivity
Human
Immunogen
CD140b-transfected NIH 3T3 cells
Target Antigen
CD140b / PDGF-RB
Clonality
Monoclonal
Clone
18A2
Applications
FACS
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
APC
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