APC Conjugated, Anti-CD117 / c-Kit Monoclonal Antibody (Clone:104D2)
CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Product Specifications
Product Name Alternative
KIT||SCFR
Gene Name
KIT
Gene ID
3815
UniProt
P10721
Host
Mouse
Reactivity
Human
Immunogen
MOLM-1 megakaryocytic cells
Target Antigen
CD117
Clonality
Monoclonal
Clone
104D2
Applications
FACS
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
APC
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