Anti-CD11c Monoclonal Antibody (Clone:BU15) -APC Conjugated
CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Product Specifications
Product Name Alternative
ITGAX||CD11C
Gene Name
ITGAX
Gene ID
3687
UniProt
P20702
Host
Mouse
Reactivity
Human, Monkey
Immunogen
Dendritic cells of synovial fluid
Target Antigen
CD11c
Clonality
Monoclonal
Clone
BU15
Applications
FACS, IP, IHC-Fr
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
APC
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