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Anti-CD122 Monoclonal Antibody (Clone:TU27) -APC Conjugated

CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.

Product Specifications

Product Name Alternative

IL2RB||IL15RB

Gene Name

IL2RB

Gene ID

3560

UniProt

P14784

Host

Mouse

Reactivity

Human

Immunogen

TL-Mor cell line

Target Antigen

CD122

Clonality

Monoclonal

Clone

TU27

Applications

FACS, IP, Functional Assay

Storage Conditions

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.

Isotype

Mouse IgG1

Conjugate

APC

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