Anti-CD206 / MMR Monoclonal Antibody (Clone:15-2) -Low Endotoxin
CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.
Product Specifications
Product Name Alternative
MRC1||CLEC13D||CLEC13DL||MRC1L1
Gene Name
MRC1
Gene ID
4360
UniProt
P22897
Host
Mouse
Reactivity
Human
Immunogen
Purified human mannose receptor
Target Antigen
CD206
Clonality
Monoclonal
Clone
15-2
Applications
FACS, IP, WB, IHC-Fr, ICC, Functional Assay
Purification
Purified by protein-A affinity chromatography
Format
Low Endotoxin
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry (frozen sections) Immunocytochemistry Functional Application blocking
Isotype
Mouse IgG1
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