Anti-CD41 / Platelet GPIIb Monoclonal Antibody (Clone:MWReg30) -Low Endotoxin
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Product Specifications
Product Name Alternative
Itga2b
Gene Name
Itga2b
Gene ID
16399
UniProt
Q9QUM0
Host
Rat
Reactivity
Mouse
Immunogen
Murine platelets
Target Antigen
CD41 (mouse)
Clonality
Monoclonal
Clone
MWReg30
Applications
FACS, IP, IHC, IHC-Fr, ELISA, Functional Assay
Purification
Purified by protein-G affinity chromatography
Format
Low Endotoxin
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Immunohistochemistry Immunohistochemistry (frozen sections) ELISA Functional Application platelet depletion
Isotype
Rat IgG1
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