Anti-CD85j / ILT2 Monoclonal Antibody (Clone:GHI/75) -Low Endotoxin
CD85j, also known as ILT-2 (Ig-like transcript 2), LIR-1 (leukocyte Ig-like receptor 1), or LILRB1 (leukocyte Ig-like receptor B1), is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Product Specifications
Product Name Alternative
LILRB1||ILT2||LIR1||MIR7
Gene Name
LILRB1
Gene ID
10859
UniProt
Q8NHL6
Host
Mouse
Reactivity
Human
Immunogen
Hairy cell leukaemia cells
Target Antigen
CD85j / ILT2
Clonality
Monoclonal
Clone
GHI/75
Applications
FACS, IP, WB, Functional Assay
Purification
Purified by protein-A affinity chromatography
Format
Low Endotoxin
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Western Blotting Functional Application blocking HLA-G induced TGF-beta1 production
Isotype
Mouse IgG2b
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