Anti-CD300e / IREM-2 Monoclonal Antibody (Clone:UP-H2) -Low Endotoxin
CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Product Specifications
Product Name Alternative
CD300E||CD300LE||CLM2||CMRF35A5||IREM2
Gene Name
CD300E
Gene ID
342510
UniProt
Q496F6
Host
Mouse
Reactivity
Human
Immunogen
CD300e-HA-transfected cells
Target Antigen
CD300e
Clonality
Monoclonal
Clone
UP-H2
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Low Endotoxin
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Western Blotting Functional Application stimulation
Isotype
Mouse IgG1
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