Anti-CD122 Monoclonal Antibody (Clone:TU27) -Low Endotoxin
CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.
Product Specifications
Product Name Alternative
IL2RB||IL15RB
Gene Name
IL2RB
Gene ID
3560
UniProt
P14784
Host
Mouse
Reactivity
Human
Immunogen
TL-Mor cell line
Target Antigen
CD122
Clonality
Monoclonal
Clone
TU27
Applications
FACS, IP, Functional Assay
Purification
Purified by protein-A affinity chromatography
Format
Low Endotoxin
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Functional Application blocking
Isotype
Mouse IgG1
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