Anti-TPX2 Monoclonal Antibody (Clone:TPX2-01)
TPX2 is a microtubule-associated protein, which is a critical regulator of mitosis. At the beginning of mitosis, TPX2 is released and plays a significant role in mitotic spindle formation and subsequent proper segregation of chromosomes during cell division. After completion of mitosis the TPX2 protein disappears, but has also role in DNA damage response. Its overexpression has been demonstrated in many types of carcinomas. TPX2 belongs to the markers of worse tumor prognosis. On the other hand, down-regulation of TPX2 can inhibit cancer cell proliferation, migration and invasion.
Product Specifications
Product Name Alternative
TPX2||C20orf1||C20orf2||DIL2||HCA519
Gene Name
TPX2
Gene ID
22974
UniProt
Q9ULW0
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Human TPX2
Target Antigen
TPX2
Clonality
Monoclonal
Clone
TPX2-01
Applications
IP, WB, IHC, ICC, ELISA
Purification
Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Immunoprecipitation Western Blotting Immunohistochemistry Immunocytochemistry
Isotype
Mouse IgG1
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