Anti-CD328 / Siglec-7 Monoclonal Antibody (Clone:6-434)
CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.
Product Specifications
Product Name Alternative
SIGLEC7||AIRM1
Gene Name
SIGLEC7
Gene ID
27036
UniProt
Q9Y286
Host
Mouse
Reactivity
Human
Immunogen
Human dendritic cells
Target Antigen
CD328 / Siglec-7
Clonality
Monoclonal
Clone
6-434
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1
Curated Selection
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