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Anti-CD206 / MMR Monoclonal Antibody (Clone:15-2)

CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.

Product Specifications

Product Name Alternative

MRC1||CLEC13D||CLEC13DL||MRC1L1

Gene Name

MRC1

Gene ID

4360

UniProt

P22897

Host

Mouse

Reactivity

Human

Immunogen

Purified human mannose receptor

Target Antigen

CD206

Clonality

Monoclonal

Clone

15-2

Applications

FACS, IP, WB, IHC-Fr, ICC, Functional Assay

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry (frozen sections) Immunocytochemistry Functional Application blocking

Isotype

Mouse IgG1

Curated Selection

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