Anti-Perforin Monoclonal Antibody (Clone:dG9)
Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9) . It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
Product Specifications
Product Name Alternative
PRF1||PFP
Gene Name
PRF1
Gene ID
5551
UniProt
P14222
Host
Mouse
Reactivity
Human
Immunogen
Purified granules from human YT lymphoma cell line
Target Antigen
Perforin
Clonality
Monoclonal
Clone
DG9
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry- intracellular staining, Immunoprecipitation, Immunohistochemistry (frozen sections), Immunocytochemistry
Isotype
Mouse IgG2b
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