Anti-GARP / LRRC32 Monoclonal Antibody (Clone:GARP5)
GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
Product Specifications
Product Name Alternative
Garpin, Glycoprotein A repetitions predominant, Leucine-rich repeat-containing protein 32, D11S833E
Gene Name
LRRC32
Gene ID
2615
UniProt
Q14392
Host
Mouse
Reactivity
Human
Immunogen
Purified human sGARP protein
Target Antigen
GARP / LRRC32
Clonality
Monoclonal
Clone
GARP5
Applications
FACS, WB
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1
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