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Anti-DLL4 Monoclonal Antibody (Clone:MHD4-46) Purified

DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.

Product Specifications

Product Name Alternative

DLL4||UNQ1895/PRO4341

Gene Name

DLL4

Gene ID

54567

UniProt

Q9NR61

Host

Mouse

Reactivity

Human

Immunogen

Recombinant soluble human DLL4

Target Antigen

DLL4

Clonality

Monoclonal

Clone

MHD4-46

Applications

FACS

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Functional Application blocking

Isotype

Mouse IgG1

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