Anti-CD195 / CCR5 Monoclonal Antibody (Clone:T21/8)
CD195 / CCR5 (also known as CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 alpha, MIP-1 beta, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 / CCR5 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
Product Specifications
Product Name Alternative
CCR5||CMKBR5
Gene Name
CCR5
Gene ID
1234
UniProt
P51681
Host
Mouse
Reactivity
Human
Immunogen
CCR5 peptide (Met1-Lys22) KLH conjugate
Target Antigen
CD195 / CCR5
Clonality
Monoclonal
Clone
T21/8
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Immunoprecipitation Western Blotting Application note:do not boil cell lysates prior to SDS-PAGE Immunocytochemistry ELISA
Isotype
Mouse IgG1
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
