Anti-TNF-alpha Monoclonal Antibody (Clone:MAb11)
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
Product Specifications
Product Name Alternative
Tumor necrosis factor, Cachectin , Tumor necrosis factor ligand superfamily member 2
Gene Name
TNF
Gene ID
7124
UniProt
P01375
Host
Mouse
Reactivity
Human, Non-Human Primates, Pig
Immunogen
Recombinant human TNF-alpha
Target Antigen
TNF-alpha
Clonality
Monoclonal
Clone
MAb11
Applications
FACS, IHC-Fr, ICC, ELISA, Functional Assay
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Isotype
Mouse IgG1
Frequently Asked Questions
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