Anti-CD18 / Integrin beta2 subunit Monoclonal Antibody (Clone:M18/2)

CD18, integrin beta2 subunit, forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18) . In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration, mediating intercellular contacts.

Product Specifications

Product Name Alternative

Itgb2

Gene Name

Itgb2

Gene ID

16414

UniProt

P11835

Host

Rat

Reactivity

Mouse

Immunogen

Murine cytotoxic T cell glycoproteins

Target Antigen

CD18 (mouse)

Clonality

Monoclonal

Clone

M18/2

Applications

FACS, IP, WB, IHC, IHC-Fr, Functional Assay

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Recommended dilution: 1 μg/mL Immunoprecipitation Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Functional Application Blocking or stimulation