Anti-HLA-B7 Monoclonal Antibody (Clone:BB7.1)
HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS) . The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.
Product Specifications
Product Name Alternative
HLA-B||HLAB
Gene Name
HLA-B
Gene ID
3106
UniProt
P01889
Host
Mouse
Reactivity
Human, Non-Human Primates
Immunogen
Papain solubilised HLA-A2, B7
Target Antigen
HLA-B7
Clonality
Monoclonal
Clone
BB7.1
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG1
Frequently Asked Questions
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