Anti-NTAL / LAB Polyclonal Antibody
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Product Specifications
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.
Target Antigen
NTAL / LAB
Clonality
Polyclonal
Applications
WB
Purification
Purified from rabbit serum by affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Western Blotting Recommended dilution: 1 μg/mL Positive control: mouse spleen
Isotype
Rabbit IgG
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