Anti-HLA-Class I Monoclonal Antibody (Clone:W6/32)

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

Product Specifications

Product Name Alternative

HLA-A, HLAA

Gene Name

HLA-A

UniProt

P01892

Host

Mouse

Reactivity

Human

Immunogen

Membrane of human tonsil cells

Target Antigen

HLA-Class I

Clonality

Monoclonal

Clone

W6/32

Applications

FACS, MC

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Immunoprecipitation Western Blotting Application note: Non-reducing conditions. Immunohistochemistry (frozen sections) Immunocytochemistry ELISA Mass Cytometry Functional Application The antibody W6/32 is suitable as a positive control for HLA tissue typing.