Anti-CD235ab / Glycophorin A Monoclonal Antibody (Clone:HIR2)

CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.

Product Specifications

Product Name Alternative

GYPA||GPA

Gene Name

GYPA

Gene ID

2993

UniProt

P02724

Host

Mouse

Reactivity

Human

Immunogen

Synthetic peptide (Human, N-terminal)

Target Antigen

CD235ab

Clonality

Monoclonal

Clone

HIR2

Applications

FACS

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry This HIR2 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes and cell agglutination assay and can be used at approximately 0.1 μg per million cells. Immunohistochemistry (frozen sections) Agglutination The antibody HIR2 agglutinates untreated RBCs but failes to agglutinate papain-treated cells.