Anti-CD41a Monoclonal Antibody (Clone:HIP8)

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

Product Specifications

Host

Mouse

Reactivity

Human, Non-Human Primates

Target Antigen

CD41a

Clonality

Monoclonal

Clone

HIP8

Applications

FACS, IHC-Fr

Purification

Purified by protein-A affinity chromatography

Format

Purified

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry This HIP8 antibody has been tested by flow cytometric analysis of human platelets. This can be used at less than or equal to 0.5 μg per 100 μl blood (per 106cells) . Immunohistochemistry (frozen sections)