Anti-CD177 Monoclonal Antibody (Clone:MEM-166)
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1) . CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN) .
Product Specifications
Product Name Alternative
CD177||NB1||PRV1||UNQ595/PRO1181
Gene Name
CD177
Gene ID
57126
UniProt
Q8N6Q3
Host
Mouse
Reactivity
Non-Human Primates, Human
Immunogen
Human granulocytes
Target Antigen
CD177
Clonality
Monoclonal
Clone
MEM-166
Applications
FACS, IP, WB
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Recommended dilution:1 μg/mL Immunoprecipitation Western Blotting Application note: Non-reducing conditions.
Isotype
Mouse IgG1
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