Anti-CD14 / LPS-receptor Monoclonal Antibody (Clone:MEM-15)
CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
Product Specifications
Product Name Alternative
CD14
Gene Name
CD14
Gene ID
929
UniProt
P08571
Host
Mouse
Reactivity
Human
Immunogen
A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
Target Antigen
CD14
Clonality
Monoclonal
Clone
MEM-15
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Recommended dilution:4 μg/mL Immunoprecipitation excellent for immunoprecipitation of CD14
Isotype
Mouse IgG1
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