Anti-CD98 Monoclonal Antibody (Clone:MEM-108)
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs) . CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Product Specifications
Product Name Alternative
Gene Name
SLC3A2
Gene ID
6520
UniProt
P08195
Host
Mouse
Reactivity
Human
Immunogen
RAJI human Burkitt's lymphoma cell line
Target Antigen
CD98
Clonality
Monoclonal
Clone
MEM-108
Applications
FACS, IP, IHC
Purification
Purified by protein-A affinity chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Flow Cytometry Recommended dilution:4 μg/mL Immunoprecipitation Immunohistochemistry Recommended dilution: 10 μg/mL Positive tissue: liver
Isotype
Mouse IgG1
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