Anti-CD70 Monoclonal Antibody (Clone:Ki-24)
CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.
Product Specifications
Product Name Alternative
CD70||CD27L||CD27LG||TNFSF7
Gene Name
CD70
Gene ID
970
UniProt
P32970
Host
Mouse
Reactivity
Human
Target Antigen
CD70
Clonality
Monoclonal
Clone
Ki-24
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Format
Purified
Components
1mg/mL, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgG3
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