Anti-PAC-1 Monoclonal Antibody (Clone:PAC-1)
CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.
Product Specifications
Product Name Alternative
DUSP2||PAC1
Gene Name
DUSP2
Gene ID
1844
UniProt
Q05923
Host
Mouse
Reactivity
Human
Immunogen
Human platelets
Target Antigen
PAC-1
Clonality
Monoclonal
Clone
PAC-1
Applications
FACS, IP, ICC
Purification
Purified from cell culture supernatant by PEG precipitation and hydroxyapatite chromatography
Format
Purified
Storage Conditions
Store at 2-8°C. Do not freeze.
Isotype
Mouse IgM
Frequently Asked Questions
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