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Azide free Anti-MHC Class II Monoclonal Antibody (Clone:M5/114)

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.

Product Specifications

Product Name Alternative

Ciita||C2ta||Mhc2ta

Gene Name

Ciita

Gene ID

12265

UniProt

P79621

Host

Rat

Reactivity

Mouse

Immunogen

Activated C57BL/6 mouse spleen cells

Target Antigen

MHC Class II (mouse)

Clonality

Monoclonal

Clone

M5/114

Applications

FACS

Purification

Purified by protein-G affinity chromatography

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Flow Cytometry Recommended dilution: 2 μg/mL Immunoprecipitation Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Functional Application Blocking of T cell proliferative responses

Isotype

Rat IgG2b

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