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Anti-CD34 / Mucosialin Monoclonal Antibody (Clone:QBEnd-10) -Azide free

CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

Product Specifications

Product Name Alternative

CD34

Gene Name

CD34

Gene ID

947

UniProt

P28906

Host

Mouse

Reactivity

Human, Non-Human Primates

Immunogen

Human endothelial vesicles

Target Antigen

CD34

Clonality

Monoclonal

Clone

QBEnd-10

Applications

Functional Assay, IP, ICC, IHC, FACS, WB, IF

Purification

Purified by protein-A affinity chromatography

Storage Conditions

Store at 2-8°C. Do not freeze.

Applications Notes

Functional application: The antibody QBEnd-10 induces homotypic adhesion of leukemic cell line. Flow cytometry: Recommended dilution: 5 μg/ml. Immunohistochemistry (paraffin sections) : Recommended dilution: 2-8 μg/ml. Western blotting: Recommended dilution: 1-2 μg/ml, positive control: TF-1 cells.

Isotype

Mouse IgG1

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